Natriumdihydrogenphosphat Dihydrat 98,0-100,5% (alkalimetrisch, berechnet an wasserfreien Substanzen), EMPROVE® EXPERT Ph. Eur., BP, USP, JPE, SAFC®

Lieferant: Merck

Synonyme: Natriumphosphat monobasisch Dihydrat

1.37018.1000EA 85.1 EUR
1.37018.1000 1.37018.9025 1.37018.9012 1.37018.5000
Natriumdihydrogenphosphat Dihydrat 98,0-100,5% (alkalimetrisch, berechnet an wasserfreien Substanzen), EMPROVE® EXPERT Ph. Eur., BP, USP, JPE, SAFC®
Natriumdihydrogenphosphat Dihydrat
Formel: NaH₂PO₄·2H₂O
Molecular Weight: 156,01 g/mol
Siedepunkt: ∼650 °C (1013 hPa)
Schmelzpunkt: 60 °C
Dichte: 1,91 g/cm³ (20 °C)
Lagertemperatur: Raumtemperatur
MDL: MFCD00149209
CAS-Nummer: 13472-35-0
EINECS: 231-449-2
REACH: 01-2119489796-13
Merck Index: 12,08806

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Spezifikation Testergebnisse

Assay (alkalimetric, calculated on dried substance) 98.0 - 100.5 %
Assay (alkalimetric; dried substance) 98.0 - 101.0 %
Identity passes test
Appearance of solution passes test
In water insoluble matter (calculated on dried substance) ≤ 0.15 %
pH-value (1 %, water) 4.1 - 4.7
pH-value (5 %; water) 4.2 - 4.5
pH-value (5.7 %; water) 4.1 - 4.5
Chloride (Cl) ≤ 0.005 %
Hydrogenphosphate (HPO₄) ≤ 0.5 %
Sulfate (SO₄) ≤ 0.01 %
Heavy metals (as Pb) ≤ 0.0005 %
Al, Ca and other elements detectable with ammonia passes test
As (Arsenic) ≤ 0.0002 %
Fe (Iron) ≤ 0.0010 %
Residual solvents (ICH Q3C) excluded by production process
Substances reducing potassium permanganate (as O) passes test
Loss on drying (130 °C) 22.0 - 24.0 %
Endotoxins ≤ 2.5 I.U./g
Total aerobic microbial count ≤ 1E+02 CFU/g
Total yeast and mould count ≤ 1E+02 CFU/g
E.coli (absent in 1g) passes test
Pseudomonas aeruginosa (absent in 1g) passes test
Staphylococcus aureus (absent in 1g) passes test
Salmonella species (absent in 10g) passes test
Bile tolerante gram negative bacteria (absent in 1g) passes test
Candida albicans (absent in 1g) passes test
DNases (Exo- and endonucleases) (not detectable) passes test
RNases (not detectable) passes test
Proteases (not detectable) passes test
Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
Corresponds to Ph Eur, BP, USP, JPE

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