Anti-BMF Rat Monoclonal Antibody [clone: 17A9]

Lieferant: ProSci
PRSI36-174EA 565 EUR
PRSI36-174
Anti-BMF Rat Monoclonal Antibody [clone: 17A9]
Antikörper
Bmf (Bcl-2-modifying factor) belongs to the Bcl-2 protein family. Bcl-2 family members form hetero- or homo-dimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. Bmf contains a single Bcl-2 homology domain 3 (BH3), and has been shown to interact with other Bcl-2 proteins and functions as an apoptotic activator. Two different start sites can give rise to two proteins of 25 or 30 kDa. It is found to be sequestered to myosin V motors by its association with dynein light chain 2 (DLC2), which may be important for sensing intracellular damage and triggering apoptosis.

Flow Cytometry: (overexpressed in cell lines). Immunoprecipitation: (1-5ug/ml). Western Blot: (1-2ug/ml).

Type: Primary
Antigen: BMF
Clonality: Monoclonal
Clone: 17A9
Conjugation: Unconjugated
Epitope:
Host: Rat
Isotype: IgG2a kappa
Reactivity: Mouse, Rat
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