Anti-NR5A2 Rabbit Polyclonal Antibody

Lieferant: ProSci
PRSI49-125EA 480 EUR
Anti-NR5A2 Rabbit Polyclonal Antibody
Alpha1-fetoprotein transcription factor (Ftf), a NR5 fushi tarazu-like receptor, also is known as ‘human B1-binding factor’ (HB1F), 'CYP7A promoter-binding factor’ (CPF), and ‘liver receptor homolog 1’ (LRH1). Ftf has been shown to affect the transcription of hepatic genes including alpha fetoprotein encoding gene (AFP), viral hepatitis B enhancer II, and 7-alpha-hydroxylase encoding gene (CYP7A1). Ftf has also been shown to affect hepatic cholesterol metabolism and bile acid synthesis. Ftf has been shown to regulate aromatase activities in adipose tissue, and alterations in Ftf expression and/or activity in adipose tissue could have considerable effects on local estrogen production and breast cancer development. LRH has been shown to expressly strongly in gonadal tissues, and may play an important role in the regulation of gonadal function. Three isoforms of Ftf have been identified: wild type (495 aa), CPF variant 1 (contains a 46-aa insertion in the A/B domain), and CPF variant 2 (contains a 172-aa deletion within the D/E domain).

NR5A2 antibody can be used in immunohistochemistry starting at 1:50, and flow cytometry.

Phosphate-buffered solution, pH 7.2, 0.09% sodium azide, 50% glycerol.

Phosphate-buffered solution, pH 7.2, 0.09% sodium azide, 50% glycerol.

Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Antigen: NR5A2
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human

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