JNK2, a MAPK type protein kinase, regulates cell apoptosis, differentiation and growth in response to growth factors, inflammatory cytokines and cellular stress. JNK2 is phosphorylated by by MKK4/MAP2K4 and MKK7/MAP2K7. Activated JNK2 translocates to the nucleus where it phosphorylates transcription factors, including c-Jun, ATF2, ELK1, Jun-D and NFAT4. At least four distinct isoforms, resulting from alternatively spliced transcript variants, have been reported - three different isoforms comprised of 382 amino acids and one comprised of 424 amino acids.
MAPK9 antibody can be used in Western Blot starting at 2 μg/mL, immunohistochemistry starting at 5 μg/mL, immunocytochemistry, and immunoprecipitation
PBS, 0.01% sodium azide, 50% glycerol.
Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.