XAB2 (XPA-binding protein 2) was first identified through its interaction with XPA. Immunoprecipitation experiments have also demonstrated that a fraction of XAB2 interacts with the transcription-coupled repair-specific proteins CSA and CSB as well as with RNA polymerase II. Microinjection experiments with XAB2 antibodies resulted in the inhibition of both transcription-coupled repair and transcription.
XAB2 antibody can be used in ELISA, Western Blot starting at 1:500 - 1:1000, immunohistochemistry starting at 5 μg/mL, and immunoprecipitation
Aliquot and store at -80°C. Avoid multiple freeze-thaw cycles.