This gene encodes a molecular chaperone that is member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of the gene described in this record have been observed but have not been thoroughly characterized.
CCT2 antibody can be used in ELISA, Western Blot starting at 1:1000, and immunohistochemistry starting at 1:50.
Phosphate-buffered solution, pH 7.2, 0.09% sodium azide at 0.5 mg/ml.
Aliquot and store at 4ºC. Avoid freezing.
Reactivity: Bat, Bovine, Dog, Gibbon, Gorilla, Hamster, Horse, Human, Monkey, Mouse, Pig, Rat, Xenopus, Zebrafish