Caveolin proteins are components of caveolae plasma membranes found in most cell types. Caveolin-3 is the muscle-specific form of the caveolin protein family whose members are proposed to be scaffolding proteins for organizing and concentrating certain caveolin-interacting molecules within the caveolae membranes. Mutations in caveolin-3 have been isolated which interfere with caveolin-3 oligomerization and disrupt caveolae formation resulting in limb-girdle muscular dystrophy.
Caveolin-3 antibody can be used in ELISA, and immunohistochemistry starting at 5 μg/mL.
Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Reactivity: Bat, Bovine, Dog, Gibbon, Gorilla, Hamster, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat