Anti-IL1A Mouse Monoclonal Antibody

Lieferant: ProSci
PRSI48-735EA 480 EUR
Anti-IL1A Mouse Monoclonal Antibody
Interleukin 1 alpha is synthesized as a 31 kDa promolecule that does not contain a signal sequence. Following proteolytic cleavage, the mature 17 kDa molecule is released as a result of cell injury or apoptosis. IL-1 alpha stimulates bone osteoclast activity, has a role in the modulation of extracellular fluid calcium homeostasis and apoptosis, activates T and B lymphocytes and NK cells, and functions in development. Movement of the IL-1 alpha promolecule to the nucleus in response to endotoxin where it augments transcription of proinflammatory genes has also been documented.

IL-1 alpha antibody can be used in ELISA, and immunohistochemistry starting at 20 μg/mL.

Protein A Column

PBS, pH 7.4, 0.03% sodium azide.

Aliquot and store at -20°C. Avoid multiple freeze-thaw cycles.

Antigen: IL1A
Clonality: Monoclonal
Conjugation: Unconjugated
Host: Mouse
Isotype: IgG2a
Reactivity: Human

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