Anti-NBN Rabbit Polyclonal Antibody

Lieferant: ProSci
PRSI48-718EA 375 EUR
Anti-NBN Rabbit Polyclonal Antibody
Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Nibrin antibody can be used in Western Blot starting at 1:1000 - 1:5000, immunohistochemistry starting at 20 μg/mL, immunocytochemistry starting at 1:100 - 1:500, immunoprecipitation, and flow cytometry.

Phosphate-buffered solution, pH 7.2, 0.09% sodium azide, 50% glycerol.

Aliquot and store at -20°C. Avoid multiple freeze-thaw cycles.

Antigen: NBN
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse

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