Duet is a TRIO/TRAD serine/threonine kinase with Dbl-Homology (DH) and Pleckstrin-Homology (PH) domains. Duet protein was localized to actin-associated cytoskeletal elements, suggesting a role in the cytoskeleton-dependent cell function. Huntington's disease is an inherited neurodegenerative disease which occurs when the widely expressed protein huntingtin contains an expanded glutamine repeat. HAPIP protein binds to HAP1, which is a huntington binding protein that may function in vesicle trafficking.
KALRN antibody can be used in immunohistochemistry starting at 20 μg/mL.
PBS, pH 7.4, 0.09% sodium azide.
Aliquot and store at -20°C. Avoid multiple freeze-thaw cycles.