TBK1, also known as NF-kappa-B-activating kinase (NAK), is an IKAPPAB type protein kinase. TBK1 protein contains a N-terminal kinase domain and two putative coiled-coil regions in the C-terminal region. It has been shown to associate with TANK and TRAF2 in a TBK1-TANK-TRAF2 signaling complex, which is believed to function upstream of the IKK complex in the TRAF-mediated activation of NF-kappaB.
TBK1 antibody can be used in ELISA starting at 1:10000, and immunohistochemistry starting at 1:200 - 1:1000.
Protein G Column
PBS, 0.2% gelatin, 0.05% sodium azide.
Aliquot and store at -80°C. Avoid multiple freeze-thaw cycles.
Isotype: IgG1 kappa
Reactivity: Gibbon, Bovine, Dog, Gorilla, Hamster, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat