Anti-MUC1 Rabbit Polyclonal Antibody

Lieferant: ProSci
PRSI48-570EA 375 EUR
PRSI48-570
Anti-MUC1 Rabbit Polyclonal Antibody
Antikörper
This gene is a member of the mucin family and encodes a membrane bound, glycosylated phosphoprotein. The protein is anchored to the apical surface of many epithelia by a transmembrane domain, with the degree of glycosylation varying with cell type. It also includes a 20 aa variable number tandem repeat (VNTR) domain, with the number of repeats varying from 20 to 120 in different individuals. The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length nature of only some has been determined. Also known as Cancer-associated Antigen 15-3 (CA15-3).

Mucin 1 antibody can be used in Western Blot, and immunohistochemistry starting at 20 μg/mL.

Affinity Chromatography

PBS, pH 7.4, 0.2% BSA, 0.05% sodium azide.

Aliquot and store at -20°C. Avoid multiple freeze-thaw cycles.

Type:
Antigen: MUC1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype:
Reactivity: Human, Mouse
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