Apoptosis antigen ligand 1 is the ligand for FAS. Both are transmembrane proteins. Interaction of FAS with its ligand is critical in triggering apoptosis of some types of cells such as lymphocytes. Defects in TNFSF6 may be related to some cases of systemic lupus erythematosus (SLE).
FASLG antibody can be used in ELISA, Western Blot starting at 1:500 - 1:1000, immunohistochemistry starting at 5 μg/mL, and immunofluorescence starting at 10 μg/mL.
PBS, pH 7.4, 0.2% BSA, 0.05% sodium azide.
Aliquot and store at 4ºC. Avoid freezing.
Reactivity: Human, Mouse, Rat