Kynurenine aminotransferase catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid. Kynurenic acid is an antagonist at the glycine site of NMDA receptors and increased levels of kynurenic acid are thought to exert a neuroprotective action in some pathological conditions.
AADAT antibody can be used in Western Blot starting at 0.5 - 2 μg/mL, immunohistochemistry starting at 10 μg/mL, and immunoprecipitation.
PBS, 0.1% sodium azide.
Aliquot and store at -80°C. Avoid multiple freeze-thaw cycles.
Reactivity: Gibbon, Gorilla, Human