Anti-ESRRG Rabbit Polyclonal Antibody

Lieferant: ProSci
PRSI48-284EA 480 EUR
Anti-ESRRG Rabbit Polyclonal Antibody
Estrogen receptor-related receptor (ERR gamma), a NR3 Steroid Receptor, has been suggested to affect differentiation of the brain, heart, and kidney. ERR gamma binds as a monomer to an extended half-site of the ERRE type (TCAAGGTCA). ERR gamma has been shown to interact with PGC-1 alpha and has been implicated in the regulation of mitochondrial energy metabolism. In humans, ERR gamma pre-mRNA undergoes extensive alternative splicing at the 5’ end, yielding at least six mRNA splice variants and two protein isoforms that differ by 23 amino acids in the N terminus. ERR gamma has been shown to be overexpressed in breast tumors, and its expression is correlated with levels of ErbB4, a likely indicator of preferred clinical course. As a result, ERR gamma has been suggested to be a potential biomarker for favorable clinical course and, possibly, hormonal sensitivity, and as a candidate target for therapeutic development.

ESRRG antibody can be used in immunohistochemistry starting at 10 - 15 μg/mL.

PBS, 0.1% sodium azide.

PBS, 0.1% sodium azide.

Aliquot and store at -80°C. Avoid multiple freeze-thaw cycles.

Antigen: ESRRG
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Reactivity: Bat, Bovine, Dog, Gibbon, Gorilla, Hamster, Horse, Human, Monkey, Mouse, Orangutan, Rabbit, Rat

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