Ionomycin CalciumsalzLieferant: MP Biomedicals
Ionomycin is an ionophore produced by the bacterium Streptomyces conglobatus.A polyether ionic antibiotic that exhibits an affinity for Ca2+. It is used in research to raise the intracellular level of calcium (Ca2+) and as a research tool to understand Ca2+ transport across biological membranes. These cytokines are important in the inflammatory response.
Ionomycin is also used to stimulate the intracellular production of the cytokines, interferon, perforin, IL-2, and IL-4 usually in conjunction with PMA.
In Ionomycin Ca2+ ionophore that is more effective than A23187 as a mobile ion carrier for Ca2+; non-fluorescent; used to study Ca2+ transport across biological membranes; induces apoptotic degeneration of embryonic cortical neurons.
Soluble in acetone, benzene, chloroform (50 mg/ml - clear colorless), DMSO (50 mg/ml - clear colourless), CHCl3 (50 mg/ml - clear colourless) and hexane all clear and colourless.
|Storage||Store at +4 °C. Protect from light|