Caerulein, sulphated

Lieferant: MP Biomedicals
ICNA02152860.5EA 284 EUR
ICNA02152860.5 ICNA0215286001
Caerulein, sulphated
Proteine und Peptide
Caerulein is a gastroregulatory molecule with actions similar to cholecystokinin. Product supplied as a trifluoroacetate salt.

Caerulein is used to study cell signaling mediated by NF-kappaB upregulation of proteins such as intercellular adhesion molecule-1(ICAM-1) and inflammation related molecules such as NADPH oxidase and Janus kinase signal transducer. It prevents gall bladder pain, renal colic, and the pain of intermittent claudication.

It is seen as an antagonist of endogenous opioids.

Soluble in ammonium hydroxide 0,05 M (1 mg/ml)(Lit.)

Sequence: pGlu-Gln-Asp-Tyr(SO3H)-Thr-Gly-Trp-Met-Asp-Phe-NH2
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