Rotenone ≥97%, weißgraues PuderLieferant: MP Biomedicals
Rotenone is a naturally occurring botanical compound obtained from the roots of Derris sp.& Cube. It is an inhibitor of mitochondrial electron transport, specifically inhibiting NAD-linked substrate oxidation by mitochondria at the oxygen side of NADH dehydrogenase.
Rotenone is utilized as an insecticide. It can be used as neurotoxic agent that can produce a Parkinson-like condition as an animal model for study of etiology and interventions.
Inhibitor of mitochondrial electron transport at NADH: ubiquinone oxidoreductase. It is readily absorbed through the exoskeletons of arthropods, but poorly absorbed cutaneously or from the gastrointestinal tract of mammals. Rotenone is used to induce a Parkinson-like syndrome as an experimental model in rats.
- Presentation: Off-White Powder
- Extinction Coefficient (E1%): 19.2 (294 nm, ethanol)(Lit.)
- Partition Coefficient: Octanol/Water Partition Coefficient-log Kow = 4.10 (Lit.)
- Optical Rotation: -120° (1.38 g/100 mL chloroform at 25 °C) (Lit.)
- Vapor Pressure: <1 x 10-5 mbar at 20 °C
- Insoluble in water; Soluble in ethanol, methanol, acetone, carbon tetrachloride, chloroform, ether, or benzene.
- Storage temperature: Room Temperature, protect from light, store under nitrogen
Molecular Weight: 394,42 g/mol
Siedepunkt: 210…220 °C (0,5 mmHg)) (Lit.)
Schmelzpunkt: 159…164 °C (Lit.)
Dichte: 1,27 (20 °C) (Lit.)
|FTIR||Conforms to Standard|