Retinsäure all-trans ≥95%, gelber FeststoffLieferant: Enzo Life Sciences
Retinoic acid receptor ligand
Retinoic acid is the active metabolite of vitamin A. It is a potent modulator of growth and differentiation exerting its effects by binding to nuclear retinoic acid receptors (RARs) which directly regulate gene expression. All trans retinoic acid binds to RAR α, β and γ subtypes with Kd values of 0.2, 0.4 and 0.2 nM respectively. RARs function as ligand-dependent transcription factors. Retinoic Acid also promotes the differentiation of mouse embryonic stem cells into adipocytes, neurons and glia in vitro. It guides development of the posterior part of the embryo.
Soluble in DMSO (25 mg/ml) or ethanol (10 mg/ml).